Ask the Experts

What Can You Tell Me About Vyvanse?

“What can you tell me about Vyvanse, the new stimulant medication?”

Vyvanse (lisdexamfetamine dimesylate) is known as a “prodrug,” meaning that it is chemically inert until it interacts with an amino acid in the gastrointestinal tract. Unlike conventional stimulants, it has no noticeable mood-altering effect if it’s crushed and snorted or injected. That suggests that it will have a lower potential for abuse. Even so, the FDA will probably classify Vyvanse as a controlled substance, like conventional stimulants. It is designed for once-daily dosing, with efficacy and side effects comparable to those of Adderall XR.

Vyvanse, which is manufactured by Shire Pharmaceuticals, went on sale in the summer of 2007.

1 Comments & Reviews

  1. This month I had a pharmacist at Walmart tell me that people CAN ‘get high’ by “snorting and crushing, injecting Vyvanse”. I’ve been telling my patients that it is a safer alternative formulation, basically the information Dr. Larry Silver has stated in this article. Has this changed? I did notice that Northpoint Washington has a blog on their addictions website that speaks to the abuse of Vyvanse by athletes and recreational abusers. While Vyvanse isn’t perfect, up till now I’ve thought it was a good option for my former addicts who have severe ADHD, or children with parents who have this history.

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