In the Spring of 2020, life turned upside down for 95% of ADDitude readers due to a global pandemic. Roughly 13% lost their jobs; 38% started working from home for the first time; and nearly 13% continued to work as essential employees. At the same time, nearly all children worldwide began learning (or trying to learn) from home. Nothing was as it had been before. The series of articles below emerged from seven surveys deployed by ADDitude during this time, and it charts the emotional, psychological, learning, treatment, and relationship ramifications of the pandemic for ADDitude readers.