Ask the Experts

Mixing Imipramine and Stimulants

“Imipramine didn’t affect my son’s ADHD, but it helped him stop wetting the bed. Can we keep him on this in addition to giving him the stimulant his doctor wants him to try?”

Imipramine enables the bladder to hold more urine at night. Often, you can discontinue imipramine after three months or so, and the bladder control will continue. If your son hasn’t reached this point, it should be all right to continue the imipramine at night while your son takes a stimulant during the day. Ask your doctor about timing and doses.

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