Medication and Treatment Reviews

Vyvanse

Generic Name: Lisdexamfetamine dimesylate

Uses

Vyvanse is a once-daily, timed-release stimulant medication primarily used to treat attention deficit hyperactivity disorder (ADHD) in children ages 6-12, adolescents, and adults. According to the FDA, Vyvanse is a federally controlled substance (CII) because it can be abused or lead to dependence. It is an amphetamine.

Vyvanse may improve focus for people with inattentive ADHD, and decrease impulsivity and hyperactive behavior, two hallmark symptoms for many patients with ADHD. It is not known if it is safe for children under the age of 6.

The American Academy of Pediatrics recommends treatment with behavioral therapy before medication for children under the age of 6. For children ages 6 to 11, the AAP says “The primary care clinician should prescribe US Food and Drug Administration–approved medications for ADHD and/or evidence-based parent- and/or teacher-administered behavior therapy as treatment for ADHD, preferably both.” Likewise, the National Institute of Mental Health finds the most successful treatment plans use a combination of ADHD medication, like Vyvanse, and behavior therapies.

Vyvanse can also be used to treat binge eating disorder in adults.

How to Use Vyvanse

Before starting or refilling a Vyvanse prescription, read the medication guide included with your pills, as it may be updated with new information.

This guide should not replace a conversation with your doctor, who has a holistic view of your or your child’s medical history, other diagnoses, and other prescriptions. If you have questions, ask your doctor or pharmacist before you begin taking the medication.

Dosage

As with all medications, follow your Vyvanse prescription instructions exactly. Vyvanse is taken orally, with or without food, once daily. The first dose is typically taken first thing in the morning; it should be taken at the same time each day for the best results.

Vyvanse is available in capsules or chewable tablets. Capsules should be swallowed whole with water or other liquids. If your child is unable to swallow the capsule, it can be opened and stirred into yogurt, water, or orange juice. Taken this way, the mixture should be swallowed entirely at once. Chewable tablets should be completely chewed before swallowing, then followed with a glass of water or other liquid.

Capsules are available in 5mg, 10mg, 20mg, 30mg, 40mg, 50mg, 60mg and 70mg dosages. Chewable tablets are available in 5mg, 10mg, 20mg, 30mg, 40mg, 50mg, and 60mg dosages.The time-release formulation is designed to maintain a steady level of medicine in the body throughout the day.

The optimal dosage varies patient by patient. Your doctor may adjust your dosage weekly by 10mg or 20mg increments until you or your child experiences the best response — that is, the lowest dosage at which you experience the greatest improvement in symptoms without side effects.  The maximum dose is typically 70mg daily.

During treatment, your doctor may periodically ask you to stop taking your Vyvanse so that he or she can monitor ADHD symptoms; check vital statistics including blood, heart, and blood pressure; or evaluate height and weight. If any problems are found, your doctor may recommend discontinuing treatment.

Some patients report developing a tolerance to Vyvanse after long-term use. If you notice that your dosage is no longer controlling your symptoms, talk to your doctor to plan a course of action.

Side Effects

The most common side effects of Vyvanse are as follows:

When treating ADHD: anxiety, decreased appetite, diarrhea, dizziness, dry mouth, irritability, loss of appetite, nausea, trouble sleeping, upper stomach pain, vomiting, and weight loss.

When treating Binge Eating Disorder: dry mouth, trouble sleeping, decreased appetite, increased heart rate, constipation, feeling jittery, anxiety.

Another serious side effect is slowed growth in children.

Taking Vyvanse may impair your or your teenager’s ability to drive, operate machinery, or perform other potentially dangerous tasks. This side effect usually wears off with time. If side effects are bothersome, or do not go away, talk to your doctor. Most people taking this medication do not experience any of these side effects.

Report to your doctor any heart-related problems or a family history of heart and blood pressure problems. Patients with structural cardiac abnormalities and other serious heart problems have experienced sudden death, stroke, heart attack, and increased blood pressure while taking Vyvanse. Stimulants can increase blood pressure and heart rate. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if you or your child experiences warning signs such as chest pain, shortness of breath, or fainting while taking Vyvanse.

Disclose to your physician all mental health issues including any family history of suicide, bipolar illness, or depression. The FDA manufacturer recommends evaluating patients for bipolar disorder prior to stimulant administration. Vyvanse may create new or exacerbate existing behavior problems, or bipolar illness. It can cause psychotic or manic symptoms in children and teenagers. Call your doctor immediately if you or your child experiences new or worsening mental health symptoms including hallucinations or sudden suspicions.

Discuss circulation problems with your doctor before taking Vyvanse, which has been known to cause numbness, coolness, or pain in fingers or toes, including Raynaud’s phenomenon. Report to your doctor any new blood-flow problems, pain, skin color changes, or sensitivities to temperature while taking Vyvanse.

Stimulants like Vyvanse have a high potential for abuse and addiction, especially among people who do not have ADHD. It is a “Schedule II Stimulant,” a designation that the Drug Enforcement Agency uses for drugs with a high potential for abuse. Other Schedule II drugs include Dexedrine, Ritalin, and cocaine. People with a history of drug abuse should use caution when trying this medication. Taking the medication exactly as prescribed can reduce potential for abuse.

The above is not a complete list of potential side effects. If you notice any health changes not listed above, discuss them with your doctor or pharmacist.

Precautions and Safety

Store Vyvanse in a secure place out of the reach of children, and at room temperature. Do not share your Vyvanse prescription with anyone, even another person with ADHD. Sharing prescription medication is illegal, and can cause harm.

You should not take Vyvanse if you are allergic to any of the ingredients in Vyavanse, or if you have taken a monoamine oxidase inhibitor (MAOI) within 14 days.

If you’re thinking of becoming pregnant, discuss the use of Vyvanse with your doctor. It is not known if it can cause fetal harm. Vyvanse is passed through breastmilk, so it is recommended that mothers do not nurse while taking it.

The safety of Vyvanse for children under age six has not been established.

Interactions

Before taking Vyvanse, discuss all other active prescription medications with your doctor. Vyvanse can have a dangerous, possibly fatal, interaction with antidepressants including MAOIs.

Vyvanse is similar to amphetamine and dextroamphetamine. You should avoid taking these medications concurrently with Vyvanse.

Share a list of all vitamin or herbal supplements, and prescription and non-prescription medications you take with the pharmacist when you fill your prescription, and let all doctors and physicians know you are taking Vyvanse before having any surgery or laboratory tests. Vyvanse can cause false steroid results.

The above is not a complete list of all possible drug interactions.

Sources:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=704e4378-ca83-445c-8b45-3cfa51c1ecad
http://www.vyvanse.com/

23 reviews

  1. We started our 10 year old son on 30 mg of Vyvanse about 3 months ago after trialing him twice on Ritalin (disastrously) with a doctor who refused to accept that Ritalin wasn’t working for him. New doctor listened and prescribed Vyvanse, which has definitely been much better for my son. His teachers report he is much better at focusing and getting work done now he’s taking this medication and I notice how much he is able to concentrate and stay calm whilst he is on it. We take it by 7am because he does have problems getting to sleep at a reasonable time otherwise. Like others have reported, there seems to be a smooth up and down with this medication. We get the odd tantrum as it’s wearing off, but nothing like on Ritalin. At first, his appetite disappeared altogether whist he was on it, but after a few weeks he was able to want to eat while he was on it. It wears off around 3.30pm (after school) and his appetite returns with a vengeance after that. So far, so good for us on Vyvanse … I just wish my son could articulate how he feels on it a little more as I have a million questions I’d like answers to (but that’s boys for you!)

  2. My son was diagnosed with ADHD at seven and been on medication ever since. He first took focalin for several years, and for last five years he has been on vyvannse. I think the effect it has is wonderful. Making him able to focus and occupy himself without excessive impulsiveness.
    However, lately we weren’t getting same results so I had doctor switch medication. First concerts but he won’t take pills so can’t review that medication. Then he put him on weak dose of Adderall. No help because it wasn’t strong enough. So I called and asked to go back to stronger dose of vyvannse. He was on one 40mg capsule daily and now it will be 50mg. I’m hoping this will be stronger. Vyvannse is great for ADHD, and I’d recommend it. From reading these reviews I’m just wondering if my son’s dose is high enough. If you find something that works it’s better to just stick with same medication and tweak dose as child ages or symtoms worsen. Which ever comes first. Only main side effects my 15 year old has is decreased appetite, irritability coming off it, and occasional stomachs aches. Glad to know Thier ISA huge ADHD community, and we are not alone!

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