ADHD Medication and Treatment Reviews


Strattera is an effective alternative to the stimulant ADHD medications most commonly used to treat symptoms of attention deficit hyperactivity disorder in children ages 6-12, adolescents, and adults.
Generic Name: Atomoxetine hydrochloride

Medically reviewed by ADDitude’s ADHD Medical Review Panel

What is Strattera?

Strattera (Generic Name: atomoxetine hydrochloride) is an alternative to the stimulant ADHD medications most commonly used to treat symptoms of attention deficit hyperactivity disorder (ADHD or ADD) in children ages 6-12, adolescents, and adults. It is a selective norepinephrine reuptake inhibitor (SNRI) medicine. Strattera is a non-stimulant; it is not considered a controlled substance by the Drug Enforcement Agency (DEA). It has not been studied in children under the age of 6.

Strattera was the first non-stimulant medication approved for ADHD treatment in the United States by the Food and Drug Administration (FDA). Stimulant ADHD medications are often the first-recommended treatment, but Strattera is a good alternative for people who cannot tolerate, or don’t experience the desired effects of, stimulant medication.

The American Academy of Pediatrics recommends ADHD treatment with behavioral therapy before medication for children under the age of 6. For children ages 6 to 11, the AAP says “The primary care clinician should prescribe US Food and Drug Administration–approved medications for ADHD and/or evidence-based parent- and/or teacher-administered behavior therapy as a treatment for ADHD, preferably both.” Likewise, the National Institute of Mental Health finds the most successful treatment plans use a combination of ADHD medication, such as Adderall XR, and behavioral therapy.

Before starting or refilling a Strattera prescription, read the medication guide included with your pills, as it may be updated with new information.

This guide should not replace a conversation with your doctor, who has a holistic view of your or your child’s medical history, other diagnoses, and other prescriptions. If you have questions, ask your doctor or pharmacist before you begin taking the medication.

What is the Typical Dosage for Strattera?

As with all medications, follow your Strattera prescription instructions exactly.  Strattera is taken orally, with or without food, once or twice daily. The first dose is typically taken first thing in the morning. If a second dose is prescribed, it is typically taken in the late afternoon or early evening. It should be taken at the same time each day for the best results.

Capsules should be swallowed whole with water or other liquids. Capsules should never be opened, crushed, or chewed. If your child is unable to swallow the capsule, discuss a different medication with your doctor.

Capsules are available in 10mg, 18mg, 25mg, 40mg, 80mg, and 100mg dosages. The time-release formulation is designed to maintain a steady level of medication in your body throughout the day.

The optimal dosage varies patient by patient. Your doctor may adjust your daily dosage after 3 days until you or your child experiences the best response — that is, the lowest dosage at which you experience the greatest improvement in symptoms without side effects. The maximum recommended dosage is 100mg/day.

During treatment, your doctor may periodically ask you to stop taking your Strattera so that he or she can monitor ADHD symptoms; check vital statistics including blood, heart, and blood pressure; or evaluate height and weight. If any problems are found, your doctor may recommend discontinuing treatment.

What Are the Most Common Side Effects Associated with Strattera?

The most common side effects of Strattera are as follows:

Children and adolescents (ages 6 – 17): upset stomach, decreased appetite, nausea, and vomiting.

Adults: constipation, dry mouth, nausea, decreased appetite, dizziness, sexual side effects, and problems passing urine.

Other serious side effects include the following: severe allergic reaction, slowed growth in children, priapism, and difficulty urinating including trouble starting and emptying the bladder. Seek immediate medical attention if you have trouble breathing, see swelling or hives, or experience any other signs of an allergic reaction.

Taking Strattera may impair your or your teenager’s ability to drive, operate machinery, or perform other potentially dangerous tasks. This side effect usually wears off with time. If side effects are bothersome, or do not go away, talk to your doctor. Most people taking this medication do not experience any of these side effects.

Disclose to your physician all mental health issues including any family history of suicide, bipolar illness, or depression. The FDA recommends evaluating patients for bipolar disorder prior to administrating Strattera to avoid inducing a manic episode. Strattera may create new or exacerbate existing behavior problems, bipolar disorder, or suicidal ideation. It can cause psychotic or manic symptoms in children and teenagers. Call your doctor immediately if you or your child experiences new or worsening mental health symptoms including anxiety, hearing voices, agitation, panic attacks, trouble sleeping, irritability, hostility, aggressiveness, or depression.

Discuss any existing liver problems with your doctor. Strattera can cause severe liver injury for some patients. Contact your doctor immediately if you or your child experiences these signs of liver problems: itching, right upper belly pain, dark urine, yellow skin or eyes, or inexplicable flu-like symptoms.

Report to your doctor any heart-related problems or a family history of heart and blood pressure problems. Patients with structural cardiac abnormalities and other serious heart problems have experienced sudden death, stroke, heart attack, and increased blood pressure while taking Strattera. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if you or your child experiences warning signs such as chest pain, shortness of breath, or fainting while taking Strattera.

The above is not a complete list of potential side effects. If you notice any health changes not listed above, discuss them with your doctor or pharmacist.

Other Precautions and Interactions Associated with Strattera

Store Strattera in a secure place out of the reach of children, and at room temperature. Do not share your Strattera prescription with anyone, even another person with ADHD. Sharing prescription medication is illegal, and can cause harm.

You should not take Strattera if you have:

  • taken, or plan to take an antidepressant monoamine oxidase inhibitor or MAOI within 14 days
  • narrow-angle glaucoma
  • an allergy to any ingredients
  • a rare tumor called pheochromocytoma

If you’re thinking of becoming pregnant, discuss the use of Strattera with your doctor. Animal studies indicate a potential risk of fetal harm; infants may be born prematurely, with low birth weight, with spinal abnormalities, or experience withdrawal. Strattera is passed through breastmilk, so it is recommended that mothers do not nurse while taking it.

The effects of Strattera on children under 6 and on the elderly have not been studied.

Before taking Strattera, discuss all other active prescription medications with your doctor. Strattera can have a dangerous interaction with antidepressants including MAOIs, asthma medicines, blood pressure medicines, and cold or allergy medicines that contain decongestants.

Share a list of all vitamin or herbal supplements, and prescription and non-prescription medications you take with the pharmacist when you fill your prescription and let all doctors and physicians know you are taking Strattera before having any surgery or laboratory tests. The above is not a complete list of all possible drug interactions.


More Information on Strattera and Other ADHD Medications:

Free Download: The Complete Guide to ADHD Medications
A Parent’s Guide to Psychiatric Medications for Children with ADHD
How Does ADHD Medication Work? Your First Questions Answered.

29 Strattera Related Links

  1. My 12 year old son has been taking Strattera for 5 weeks now. He started with 2 weeks of 10mg then moved up to 18 mg and he will be on that for another week before ramping up again. He has had no side effects so far. I think we are finally starting to see some improvement in his symptoms after 5 weeks…he seems calmer and more focused. We are giving him the Strattera every night after dinner. He sleeps great at night and has had no stomach problems. I did notice that he seemed a little more anxious and withdrawn after starting the 10 mg and again after starting the 18 mg but that went away after about 3 days. My son moved up to the 25 mg dose last Friday. On Saturday he seemed more unfocused. There did not seem to be any extra anxiety or any other side effects this time.

  2. My 8 year old daughter was taking two 25mg pills every morning and then Intuniv 3mg at night. She started having severe stomach cramps daily. We switched the Strattera to 25mg in the morning and 25mg at night and now she rarely has stomach cramps.

  3. My son takes Straterra and we are having success with one exception, stomach problems. The problem was the dye used in the capsules and not the medication itself.

  4. My 9 year old daughter is up to 25 mg of Strattera. However, there are some nights when she wakes up in the middle of the night and cannot fall back to sleep for long periods of time.

  5. I am male and 55 years old recently diagnosed with ADHD. I am on 80 mg of Strattera. It has helped much with anxiety and impulsivity. I am having negative side effects: I feel more spacey, food tastes bland and my appetite has decreased.

  6. I am 39 and newly diagnosed. I started on Strattera this past weekend and am on 40 mg twice a day as of two days ago. I was very drowsy the first two days, but it hasn’t been that bad since. On the other hand, I haven’t noticed much other difference in my attention or organizational capacity, either.

  7. I am taking 18mg once per day and this is the second week. The first week I had insomnia like crazy and lately I have been sleeping more than ever in my life.

  8. I am 56 year old Retired Special Ed teacher, and have been taking 40mg BID Strattera for over 5 years—works great for me. However, I did develop a small facial tic (excessive eye blinking).

  9. I am a 52 year old female with ADHD, and I take 60mg of Strattera daily, and the only problem I have with mine is occasionally I have dry cotton mouth. I have been taking it now for 5 years.

  10. I am on 40mg Strattera as well as 30mg Vyvanse. The first few weeks of Strattera were a little rocky, but four months into it, I am very pleased with it. However, the Vyvanse gets me motivated and the Strattera helps me to focus.

  11. I started at 40 mg and had a crazy over-the-top response to it (stared at a wall in bed for several hours). Now I’m on 10 mg. If I take it at night (after 5:00pm), I feel pretty good except for a little dry mouth and insomnia. However if I take it first thing in the morning, I spend the majority of the morning and early afternoon exhausted and kind of out of it.

  12. I’m 38 years old. And last month I diagnosed ADHD. I started Strattera 40mg, I don’t have a effectiveness yet, but I feel very strong sleepiness all day as side effect.

  13. I started at 18mg and worked up to 60mg over the course of a month. I felt restless and cranky all the time. However, now that it is fully kicked in (I’ve been on it for about 4 months), it is worth it.

  14. My 8 yr old was on Strattera for several months. Starting low at 10, increasing to 10 at night and 10 at morning, to 18 at night and 25 in the morning. It worked wonders for her ADHD combined type. Inattentive and impulsive at school, and impulsive and struggling with behavior at home. Initially, she was extremely tired the first two weeks. Thankfully we started it over a school break, but she napped for hours every mid day. After it built up, it made her very calm and focused and she teacher noticed a great improvement. Although maybe a little too calm for my liking. She wasn’t walking around like a zombie, but she just wasn’t as vibrant as before, so I was on the fence. She was still eating and playing like a normal child. We stayed on it because she in her own words, liked how she didn’t feel so crazy inside. However, it caused stomach issues early on. She would vomit about a hour after taking her medication. This happened 5-6 separate occasions. We did quickly learn that a high fat high protein breakfast remedied that. But as we increased the dosage, the stomach issues increased as well. Stomach aches and headaches that wouldn’t go away made it hard to get her to want to take her meds. We took the summer off then ended up switching.

  15. My 13 year old daughter takes strattera. At first it gave her severe stomach pain and she felt like she was going to throw up. She barely ate anything for weeks. Then those problems decreased, and she rarely experiences those side effects anymore. It has been very helpful and we have seen much improvement in her focus and all areas in her life.

  16. After being given a sample prescription and reading up on it I had real concerns and did not take it. I fought (with knowledge) for a main line treatment for adhd (adderall) and am fully satisfied. The only real reason I could find why they would prescribe this is that it has low potential for abuse. It is far less likely to work and because it is stimulant like it carried the same or worse cardiac risk. You need to focus your hyperactivity on learning, do not trust that your doctor is up to speed, and be sure to explain how severe your condition is to you because most doctors think adhd is minor and not worth any risk to treat.

  17. Started Strattera this morning as my first attempt to treat my recently diagnosed ADD. I am a 43-year-old woman. My response was very negative to this medication. Approximately 1 to 2 hours after taking it I became extremely exhausted, dizzy, dry mouth, and slurred speech. I also had moments of feeling “high” -but not the good kind. It felt like I was floating, accompanied by small episodes of anxiety.These effects lasted throughout the day on and off for several hours and into the evening. I took only 25 mg to start. I cannot imagine trying to ride this out as it made me a completely nonfunctional person as a mom of three kids I can’t afford to wait weeks or a month for the symptoms to resolve or decrease. Awful 🙁

  18. Strattera is something to be careful with. I have definitely read several good reviews and heard other people talk about Strattera being effective, but it must vary from one individual to another for some reason, and it seems to me that for some people it works really well and for others it causes an enormous negative disruption in the patient’s mental state. During a quest to find better medication after Concerta didn’t seem to affect me as well as it did when I was younger, I tried Strattera briefly. I don’t remember the specific dosage but I know it was pretty low (probably either 10mg or 18mg) , and I was instructed to take one pill every day for a week, and then start taking two pills a day, at which point I would be at the minimum recommended dose for my weight, age, symptom severity, etc. During the week that I took one pill I didn’t notice much in the way of changes to my behavior or symptoms, which wasn’t much of a surprise because in the past I took pretty high dosages of other medications. The first day that I took two started out okay, but all day at work I felt some tension building, and around 3 o’clock I just went haywire: I felt irrationally angry and ready to get in a fight with the next person who spoke to me. I left work around that time because it was the end of my shift, and luckily it was only a five minute drive home because I after arriving at home I proceeded to succumb to a full-blown mental breakdown, for which there was no apparent catalyst. I figured perhaps I just wasn’t used to the drug yet, and continued to take it the same way for the next week or so. Although the side effects were not as severe in that following week, I would get into an argument or transition into a mood that I can describe as having been- depending on the day- anywhere from just irritable to “rage mode” every day around the same time (3 o’clock/mid-afternoon), and it would last until the medication wore off. I have several friends who are also AD/HD and those of them who have tried Strattera have had similar experiences. I have nothing against the medication, if it works for a person then it works, however please be careful with it and pay close attention to any behavioral changes like this, because chances are it is not “just a bad day/week” and this is not the appropriate medication.

  19. I’m a 56 y.o. male, diagnosed with ADHD, ODD, Depression. Been on Strattera for ~ a year. Started out with 80mg, did great, then felt after about 3 months, my focus started slipping. Bumped it to 100mg, and felt an edginess to my mood. Backed off to 80mg again. Can’t take any amphetamine based meds because it causes joint pain. Strattera for me has had some side-effects: bladder tingle, trouble urinating. Also, increase libido and ejaculation before actual climax. No kidding. For the most part, I’ve been pretty happy with the increased focus.

Tips for Good Medication and Treatment Reviews

  • Post reviews only for medications or treatments you have used or prescribed.
  • In your description, mention whether you're reviewing the medication or treatment for a child or for an adult (yourself or another adult), and as a patient or as a medical professional.
  • Mention what medical condition you were using the medication or treatment to address.
  • Mention the brand, dose, and period of time that you used the medication or treatment.
  • Please share your positive and negative experiences with the medication or treatment in detail. Note effectiveness, ease of use, side effects; and compare it with other treatments you have used.
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