Generic Name: Guanfacine
Intuniv, known as guanfacine in its generic forum, is a once-daily, non-stimulant medication used to treat ADHD in children ages 6-12, adolescents, and adults. It is commonly used as a monotherapy, or as a complementary treatment alongside stimulant medications.
Intuniv is a central alpha2A-adrenergic receptor agonist that is thought to affect receptors in the brain in a way that helps symptoms of ADHD such as emotional sensitivity, hyperarousal, and social aggression. Non-stimulant medications like Intuniv sometimes help patients with ADHD who can’t take or don’t experience benefits from stimulants.
Intuniv has not been studied in children younger than 6. Intuniv does not have a high risk of abuse or dependence. It is not a controlled substance.
The immediate-release formulation of guanfacine is used to treat high-blood pressure.
How to Use Intuniv
Before starting or refilling an Intuniv prescription, read the medication guide included with your pills, as it may be updated with new information.
This guide should not replace a conversation with your doctor, who has a holistic view of your or your child’s medical history, other diagnoses, and other prescriptions. If you have questions, ask your doctor or pharmacist before you begin taking the medication.
As with all medications, follow your Intuniv prescription instructions exactly. Intuniv is an extended-release tablet taken once daily in the morning or evening at approximately the same time each day. Tablets are available in 1mg, 2mg, 3mg, and 4mg dosages.
Intuniv should not be taken with a high-fat meal. This can speed up the release of medication, and increase the risk of side effects. Tablets should be swallowed whole, and never crushed or chewed.
The optimal dosage varies patient by patient. Your doctor may adjust your dosage weekly by 1mg increments until you or your child experiences the best response — that is, the lowest dosage at which you experience the greatest improvement in symptoms without side effects.
If you miss a dose, you should take it as soon as possible, unless it is already time for your next dose. You should not take two doses of Intuniv at the same time. Contact your doctor if you have questions about skipped pills.
Do not drink alcohol while taking this drug.
When discontinuing treatment, or decreasing dosage, patients should work with a doctor to gradually taper the level of medication by no more than 1mg every 3 to 7 days. Stopping Intuniv suddenly can create withdrawal symptoms including increased heart rate and high blood pressure, sometimes accompanied by headaches, confusion, agitation, or tremors.
The most common side effects of Intuniv are as follows: sedation, tiredness, difficulty sleeping, low blood pressure, nausea, stomach pain, dizziness, dry mouth, irritability, vomiting, and slow heart rate.
Other serious side effects include low blood pressure or heart rate, fainting, sleepiness, or withdrawal symptoms. Taking Intuniv may impair your or your teenager’s ability to drive, operate machinery, or perform other potentially dangerous tasks. If side effects are bothersome, or do not go away, talk to your doctor. Most people taking this medication do not experience any of these side effects.
Report to your doctor any heart-related problems or a family history of heart and blood pressure problems. Patients with structural cardiac abnormalities, renal failure, and serious heart problems could experience complications while taking Intuniv. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if you or your child experience warning signs such as chest pain, shortness of breath, or fainting while taking Intuniv.
The above is not a complete list of potential side effects. If you notice any health changes not listed above, discuss them with your doctor or pharmacist.
Precautions and Safety
Store Intuniv in a secure place out of the reach of children, and at room temperature. Do not share your Intuniv prescription with anyone, even another person with ADHD. Sharing prescription medication is illegal, and can cause harm.
You should not take Intuniv if you have an allergy to Intuniv or any of its ingredients. You should use caution taking Intuniv if you have kidney problems, a history of fainting, heart problems, or a history of stroke.
Avoid becoming overheated or dehydrated while taking Intuniv.
If you’re thinking of becoming pregnant, discuss the use of Intuniv with your doctor. Animal studies indicate a potential risk of fetal harm. It is not known if Intuniv is passed through breastmilk, so it is recommended that mothers do not nurse while taking it.
Before taking Intuniv, discuss all other active prescription medications with your doctor. Intuniv can exacerbate the drowsiness created by depressants including alcohol, barbiturates, antihistamines, or other sedatives.
Share a list of all vitamin or herbal supplements, and prescription and non-prescription medications you take with the pharmacist when you fill your prescription, and let all doctors and physicians know you are taking Intuniv before having any surgery or laboratory tests. The above is not a complete list of all possible drug interactions.
Tips for Good Medication and Treatment Reviews
- Post reviews only for medications or treatments you have used or prescribed.
- In your description, mention whether you're reviewing the medication or treatment for a child or for an adult (yourself or another adult), and as a patient or as a medical professional.
- Mention what medical condition you were using the medication or treatment to address.
- Mention the brand, dose, and period of time that you used the medication or treatment.
- Please share your positive and negative experiences with the medication or treatment in detail. Note effectiveness, ease of use, side effects; and compare it with other treatments you have used.
- Do not include any personal information or links in your review.