ADHD Medication and Treatment Reviews

Cotempla XR-ODT

Cotempla XR-ODT is the first methylphenidate-based extended-release orally disintegrating tablet for the treatment of ADHD in kids ages 6-17.
Generic: methylphenidate

What is Cotempla XR-ODR?

Cotempla XR-ODT (General Name: methylphenidate) is the first methylphenidate-based extended-release orally disintegrating tablet for the treatment of ADHD in children between the ages of 6 and 17. Cotempla XR-ODT contains the same active ingredient as medications like Ritalin and Daytrana, but it dissolves in the patient’s mouth, without chewing or drinking water. According to the FDA, Cotempla XR-ODT is a federally controlled substance (CII) because it can be abused or lead to dependence. The safety and effectiveness of Cotempla XR-ODT has not been established for children under the age of 6.

The National Institute of Mental Health finds the most successful treatment plans use a combination of ADHD medication, like Cotempla XR-ODT, and behavior therapies.

How Do You Use Cotempla XR-ODT?

Before starting or refilling a Cotempla XR-ODT prescription, read the medication guide included with your child’s pills, as it may be updated with new information.

This guide should not replace a conversation with your child’s doctor, who has a holistic view of your or your child’s medical history, other diagnoses, and other prescriptions. If you have questions, ask your doctor or pharmacist before your child begins taking the medication.

What is the Typical Dosage for Cotempla XR-ODT?

As with all medications, follow your Cotempla XR-ODT prescription instructions exactly. Cotempla XR-ODT is taken orally, once daily in the morning with or without food and water.

Tablets are available in 8.6mg, 17.3mg, and 25.9mg tablets. The time-release formulation is designed to maintain a steady level of medication in your child’s body throughout the day.

The optimal dosage varies patient by patient. Your doctor may adjust your child’s daily dosage until your child experiences the best response — that is, the lowest dosage at which your child experiences the greatest improvement in symptoms without side effects.

Cotempla XR-ODT is a grape-flavored quick-dissolving tablet. To keep it from dissolving before your child places the tablet in the mouth, leave it contained in its blister package until your child is ready to take it. When opening the medication, make sure your hands are clean and dry so as not to accidentally trigger dissolution. Peel back the blister package backing to take out the tablet instead of pushing it through the foil. Place the tablet on your child’s tongue to dissolve. Do not crush or chew the tablet.

Your teen should not drink alcohol while taking this medication.

During treatment, your doctor may periodically ask your child to stop taking Cotempla XR-ODT so that he or she can monitor ADHD symptoms; check vital statistics including blood, heart, and blood pressure; or evaluate height and weight. If any problems are found, your doctor may recommend discontinuing treatment.

Some patients report developing a tolerance to Cotempla XR-ODT after long-term use. If you notice that your child’s dosage is no longer controlling symptoms, talk to your child’s doctor to plan a course of action.

What Side Effects are Associated with Cotempla XR-ODT?

The most common side effects of Cotempla XR-ODT are as follows: decreased appetite, difficulty sleeping, nausea, vomiting, stomach ache, abdominal pain, weight loss, anxiety, dizziness, mood swings, increased blood pressure, and irritability.

Other serious side effects include slowing of growth in children, blurred vision, and priapism.

If side effects are bothersome, or do not go away, talk to your child’s doctor. Most people taking this medication do not experience any of these side effects.

Report to your doctor any heart-related problems or a family history of heart and blood pressure problems. Patients with structural cardiac abnormalities and other serious heart problems have experienced sudden death, stroke, heart attack, and increased blood pressure while taking Cotempla XR-ODT. Stimulants can increase blood pressure and heart rate. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if your child experiences warning signs such as chest pain, shortness of breath, or fainting while taking Cotempla XR-ODT.

Also disclose to your physician all mental health issues including any family history of suicide, BPD, or depression. Cotempla XR-ODT may create new or exacerbate existing behavior problems or BPD. The manufacturer recommends evaluating patients for risk factors for developing a manic episode prior to treatment. Call your doctor immediately if your child experiences new or worsening mental health symptoms including hallucinations or sudden suspicions.

Discuss circulation problems with your doctor before taking Cotempla XR-ODT, which has been known to cause numbness, coolness, or pain in fingers or toes, including Raynaud’s phenomenon. Report to your child’s doctor any new blood-flow problems, pain, skin color changes, or sensitivities to temperature while taking Cotempla XR-ODT.

Stimulants like Cotempla XR-ODT have a high potential for abuse and addiction, especially among people who do not have ADHD. It is a “Schedule II Stimulant,” a designation that the Drug Enforcement Agency uses for drugs with a high potential for abuse. Other Schedule II drugs include Dexedrine, Ritalin, and cocaine. People with a history of drug abuse should use caution when trying this medication. Taking the medication exactly as prescribed can reduce the potential for abuse.

The above is not a complete list of potential side effects. If you notice any health changes not listed above, discuss them with your doctor or pharmacist.

What Precautions are Associated with Cotempla XR-ODT?

Store Cotempla XR-ODT in a secure place out of the reach of children, and at room temperature. Your child should not share a Cotempla XR-ODT prescription with anyone, even another person with ADHD. Sharing prescription medication is illegal, and can cause harm.

Patients should not take Cotempla XR-ODT if they have an allergy or hypersensitivity to Cotempla XR-ODT or any of the ingredients in Cotempla XR-ODT medication, or if they have taken monoamine oxidase inhibitors (MAOIs) within 14 days.

Use caution while taking Cotempla XR-ODT if your child has a history of heart or mental problems or circulation problems.

There are risks associated with taking methylphenidate during pregnancy. If your teen becomes pregnant, discuss the use of Cotempla XR-ODT with your doctor. Cotempla XR-ODT is passed through breastmilk, so it is recommended that mothers do not nurse while taking it.

The safety of Cotempla XR-ODT for children under age six has not been established.

What Interactions are Associated with Cotempla XR-ODT?

Before taking Cotempla XR-ODT, discuss all other active prescription medications with your child’s doctor. Cotempla XR-ODT can have a dangerous, possibly fatal, interaction with antidepressants including MAOIs.

Your child should not take gastric pH modulators (e.g., an H2-blocker or proton pump inhibitor, like Prilosec).

Share a list of all vitamin or herbal supplements, and prescription and non-prescription medications your child takes with the pharmacist when you fill the prescription, and let all doctors and physicians know your child is taking Cotempla XR-ODT before having any surgery or laboratory tests. The above is not a complete list of all possible drug interactions.


More Information on Cotempla XR-ODT and Other ADHD Medications:

A Parent’s Guide to ADHD Medications
Free Download: The Complete Guide to ADHD Medications
The Full Range of Treatment Options for Children with ADHD
Primer: The Stimulant Medications Used to Treat ADHD

5 Cotempla XR-ODT Comments & Reviews

  1. I understand its early to add a review, but I thought I would since there are non available. I was able to get the first month free with a coupon. I’m 42 years old and was able to use the coupon even though it said only good for ages 6-17. The medication does dissolve on my tongue. It has a nice grape flavor. If you are sensitive to fake med tastes you might not like it. It takes about 30 seconds to be completely dissolved. It came on strong for the first hour. Then it evens out. I was able to eat after taking it with no problems. So far it seems to be helping with keeping me focused. If I was a child taking it I probably wouldn’t mind the taste. It might be a good idea to give it to a child when they first wake up and then let them sit and eat something while the medication evens out. It might help to let them watch TV so by the time a half hour show is over the medication has settled down. As I take this more I will edit my review.

  2. Quick history:

    Diagnosed at 14 years old. Briefly medicated in High School. Attempted to treat for about a year when I was 28. Lost insurance and did not come back to treatment until I was 35.


    I am now a 37 year old adult who had previously been taking Concerta. That had been working great for over a year. Recently, I started noticing a decline in effectiveness with the 54mg of Concerta that I was taking. I had been a smoker for 23 years. I quit smoking around the same time that I started noticing the decline. I do not know if that was just coincidence or not.

    My doctor asked if I would try Cotempla instead. He placed me on a double 25.9mg dose, which is slightly less than then 54mg I was previously taking. I have been taking it now for almost a month.

    So far, I feel like I am slowly heading back to the place I was before taking Concerta. I am often finding myself back in a foggy state. I seem to have a burst of focus in the morning but by noon, I am struggling to focus on any one task. Due to that, I am finding myself having great anxiety about not accomplishing what I need to do.

    During the time that Concerta was effective; I was having great success. I was managing to accomplish great things at work. I was prioritizing and very focused. I was almost always finished with everything I needed to do by 5pm. It was a GREAT feeling! Now, I am drifting so much that I am having to work in the evenings and weekends to make up for the time I drift. This also causes me to lose sight of not work things. So, I am in a cycle of feeling behind both personally and at work.

    To be quite honest, I was struggling to even complete this review.

    I am curious if any other ADHD adult has had this experience with Cotempla or in general?

  3. I’ve been taking Contempla at the lowest dose for 4 weeks now,at first it worked as it should,it helped with most of the symptoms related to my ADHD,its been 4 weeks as I mentioned before and this is how I feel at the 4 week mark.

    when I take the medication and place it under my tongue it dissolves with in 30 seconds and takes a good hour or so to kick in,for a good two hours after I has started working I feel a huge rush of euphoria and can definitely tell the medication is working,after two hours the feeling of being really medicated does down and the medication levels out for a couple of hours before wearing off a bit does not help me focus of things that need to get done as much as it did in the begining,but it’s not to bad.i have a loss of appetite but have managed that quite well by eating as much as possible and I try to drink as much as I can during the day,water that is.the medication does cause anxiety as I also suffer anxiety and have for years,but I’m learning to control that own my own,but fo take a benzo from time to time when my anxiety sparks.

    the medication wears off around 3:30 and some days I notice it and some days I dont.ive tried swallowing the pill while as letting it dissolve on top of my tongue and have found the best way is is on top of the tongue,as ir does not hit me as hard as it would when taken under the tongue but is not as effective during the day as when taken under the tongue.i want to continue taking this medication for a bit longer as I feel it’s worked the best for me.ive tried 5 other meds for ADHD qnd have found this one to work best

  4. 2 of my kids are on this medicine. We switched hoping for a less expensive option to Focalin XR which worked great but became so expensive & was increasingly hard to find.

    My 13YO tried the 17.3mg in Nov. ‘17. It didn’t work, but we increased the dose to 25.9mg. He seemed to level off & made honor roll for the 1st time ever during 3rd quarter at school. We were very enthusiastic about it. By 4th quarter, his grades included D’s & F’s. We chalked it up to Fortnite & some other personal things. Before the school year ended it was bad- lots of missing assignments again. He was able to finish the quarter with all As, except 1 D. Summer was as bad or worse even without the schoolwork.

    We just started the new school year and at 2.5wks in, his grades are terrible. Lots of missing assignments & struggles in subjects he aced previously. I tried to attribute it to him needing extra help, except he never even bothered to access his online book. 🙁

    Behaviorally at home, he’s been a nightmare. It’s too much to chalk up to hormones or typical 13YO boy stuff. He’s rude, lies and is oppositional about stuff that’s ridiculous. Screaming, crying and being physically & verbally aggressive with his little sisters was the final straw. We’re headed back to our pediatrician & switching back to Concerta or generic Focalin.

    Our 10 YO tried Cotempla 17.9mg 1st at the same time as her brother to save money. It was pretty bad after 1wk & we switched her back to Dexmethylphenidate. She finished the school year, achieved great results on our state assessment and tested into the gifted program. We decided to try again over summer. She switched OK, then the school year started. I didn’t know how she was doing because of the way our school grades work. I found out yesterday she has 6 missing assignments & her teachers are saying she’s lost in space a lot these days.

    Behaviorally, it was the same at home. Her room is a disaster, she cries a lot, etc. I switched her back to Dexmethylphenidate today and saw a big difference already. I wanted to like Cotempla, but the cons outweigh the pros after a short time. We’ll stick with the more reliable ones. I wish Focalin brand was less expensive. It’s been the best, but was so expensive I felt we were going brankrupt on meds.

  5. So sorry it wasn’t a good fit but hoping things continue to improve after switching your kids back to other meds.
    My 12-year-old son has been on cotemplata Xr 25.9 for 4 months – switched from Focalin XR 20 mg with reg Focalin 5 mg lunchtime booster. We noticed a subtle improvement w/ Cotempla. Lasts longer so homework battles are gone most eves. He’s also on Zoloft 125 mg for anxiety/depression to help w/ at-home nightmare behavior. Both meds combined, coupled with “Love and Logic” – ish parenting approach and LOTS of outdoor unstructured free time has helped. It’s never one thing that our kids struggle with and it’s never one thing that fixes everthing. And one sizie does NOT fit all. These ADHD meds are like jeans. A pair may look awesome on one person and terrible on another. Sigh. Soldier on, parents.

Tips for Good Medication and Treatment Reviews

  • Post reviews only for medications or treatments you have used or prescribed.
  • In your description, mention whether you're reviewing the medication or treatment for a child or for an adult (yourself or another adult), and as a patient or as a medical professional.
  • Mention what medical condition you were using the medication or treatment to address.
  • Mention the brand, dose, and period of time that you used the medication or treatment.
  • Please share your positive and negative experiences with the medication or treatment in detail. Note effectiveness, ease of use, side effects; and compare it with other treatments you have used.
  • Do not include any personal information or links in your review.

Add Your Review