The Daily Essential Nutrients uses the methylated forms of B12 and folate, so it is safe for the MTHFR genetic mutation. It is also the only multivitamin mineral supplement to date that has a double blind study on pediatric ADHD, which you can learn more about on Hardy Nutritionals website. Fyi
Daily Essential Nutrients has been a game changer for our family. It has allowed my son to overcome a long list of symptoms which return when he misses a few doses. Biggest changes I notice are: reduction in aggression, better attitude, easier rebound from change in schedule, reduced to 0 arm flapping, and he sleeps better. His teacher is amazed at how he is doing this year in school because his teacher last year warned her (before he started Daily Essential Nutrients) that he would be out of control. Not one issue this year.