There are people who experience this consistent failure of medications. Could be metabolism or genetics, or both. Sometimes it’s a separate biological issue, like a food intolerance.
Sometimes you have to try several medications to find one that is effective for you:
Here’s a primer on ADHD medication to help you know what medication options are out there:
ADDitude Community Moderator, Parenting ADHD Trainer & Author, Mom to teen w/ ADHD, LDs, and autism