Reply To: Switching to Adderall

Penny Williams

ADHD stimulant medication is very individualized. Dosage depends on neurotransmitter needs, metabolism, and genetics of each individual. So, the dose of Adderall that works for one child may likely not work at all for another. Here’s a really thorough primer on ADHD medication that explains this and more:

A Patient’s Primer on the Stimulant Medications Used to Treat ADHD

You have to take the Genesight results with a grain of salt. These tests only determine which medications an individual might be genetically predisposed to have a bad reaction to. The test doesn’t account for any other factors that determine the efficacy of ADHD medication for a particular individual. My son has had rare and severe reactions to SSRI’s tried to treat his anxiety over the years, as well as some stimulants. When these tests hit the market I was very eager to try it and see what medications we could add to our “avoid” list. We did GeneSight and one other and both came back with zero issues on every medication, even that list of 5-6 that he had already had serious reactions to. These tests are great for those with genetic abnormalities that would make certain medications intolerable, but they are just one small piece of the puzzle.

With the Adderall now, you may need an increase in dosage again. The standard of care is to start at the lowest dose and only increase if and when necessary. Here’s a great webinar replay on getting ADHD medications right:

Free Webinar Replay: Medication Management: How to Use and Adjust Stimulants Safely

ADDitude Community Moderator, Author & Mentor on Parenting ADHD, Mom to teen w/ ADHD, LDs, and autism