Reply To: Medication not working, please help!

Home Welcome to the ADDitude Forums For Adults Medication not working, please help! Reply To: Medication not working, please help!

#195161
WaveOffTheCoast
Participant

Not sure if this it’s helpful, but I was out on Vyvanse (Elvanse) for a while. Even up to the maximum dose, I felt nothing. But Adderall (amphetamine salts) work for me. My doctor explained that Vyvanse is dextroamphetamine with an amino acid attached (lysine). Enzymes break the amino acid off to make the drug available. My psychiatrist had noticed certain patients seemed to have no response. He suspected that maybe the enzyme wasn’t breaking the lysine off properly.

All that is to say, if Vyvanse works for you, you should notice a difference that day. If it doesn’t, there are other versions of amphetamine based drugs that might work better for you.