I have always had a bad reaction to progesterone, all forms. They even tried a synthetic form on me. The day after I begin progesterone,I cry, cry, cry. Depression gets worse. It took years to find an MD who would put me on unopposed beta-estradiol. It was essential for my mental, improving Adhd brain functioning enormously.
At menopause, I became deeply depressed. Estradiol saved my life.
My new MD took me off it a year ago and I have been struggling. I will be asking my MD to restart the estrogen but most MDs have no clue…Estrogen is incredible beneficial to all manner of BRAIN FUNCTION: memory, executive functions, and mood improvement.