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Hello! I’m glad I saw your post as I just dealt with this situation. I had to switch from adderall XR to vyvanse while taking Paxil, as the adderall was not working. From what I understood, it is something to do with the formulation of the Paxil and increasing the adderall dosage doesn’t help. In addition, my doctor had me take Paxil in the evening to help with the drowsiness. Vyvanse worked well with Paxil, but I did have a dosage adjustment after that. I hope this helps! Good luck!