Definitely could be depression. It’s time to see a clinician or therapist and talk about how you’re feeling.
Also, from an outside perspective, it sounds like looking for a job in your hometown might be ideal for you. What you’ve described is that not being where you have friends and family and familiarity is making you sad (and exhausted). It’s important to outline what you find most important in your life and work toward those things. Then find a job that can support you in these other goals.
ADDitude Community Moderator, Parenting ADHD Coach & Author, Mom to teen w/ ADHD, LDs, and autism