My doctor told me from the beginning of my son’s medication that I needed to take 48 hours off every week for maximum efficacity. And my son’s appetite also returns to voracious during the 48 hour med rest.
My son has a mild appetite and going off the meds at the weekend is important.
As far as dossage: I am 176 pds and take one 36mg time release concerta and my son (11 years) at 62 pounds takes one 18mg time release in the morning.
Hope this might give you a comparison.