The cbd has no side effects with my daughter’s medication (Zoloft and trazadone). There are no real side effects from cbd that I’ve seen at all, except decreased anxiety and depression and less ocd ticks…lol! CBD is legal in most states as it does not have THC, no age issues. My daughter’s therapist and pyschiatrist are excited that we are using it as it is helping so much. She uses the water soluble for her doses and we bought the gummies to take with us in case of severe anxiety attacks.