"My eight-year-old son is taking 17.5 mg of a slow-release stimulant, and has become very irritable. He weighs about 50 pounds. Is his dosage too high — and is this behavior change normal?"
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http://www.additudemag.com/q&a/ask_the_add_medical_expert/1236.html
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ADD Meds: Dosing
Ritalin