"What can you tell me about Vyvanse, the new stimulant medication?"
Larry Silver, M.D.
Vyvanse (lisdexamfetamine dimesylate) is known as a “prodrug,” meaning that it is chemically inert until it interacts with an amino acid in the gastrointestinal tract. Unlike conventional stimulants, it has no noticeable mood-altering effect if it’s crushed and snorted or injected. That suggests that it will have a lower potential for abuse. Even so, the FDA will probably classify Vyvanse as a controlled substance, like conventional stimulants. It is designed for once-daily dosing, with efficacy and side effects comparable to those of Adderall XR.
Vyvanse, which is manufactured by Shire Pharmaceuticals, went on sale in the summer of 2007.