What can you tell me about Vyvanse?


"What can you tell me about Vyvanse, the new stimulant medication?"

Dr. Larry Silver specializes in treating children with attention deficit disorder (ADHD).

Vyvanse (lisdexamfetamine dimesylate) is known as a “prodrug,” meaning that it is chemically inert until it interacts with an amino acid in the gastrointestinal tract. Unlike conventional stimulants, it has no noticeable mood-altering effect if it’s crushed and snorted or injected. That suggests that it will have a lower potential for abuse. Even so, the FDA will probably classify Vyvanse as a controlled substance, like conventional stimulants. It is designed for once-daily dosing, with efficacy and side effects comparable to those of Adderall XR.

Vyvanse, which is manufactured by Shire Pharmaceuticals, went on sale in the summer of 2007.

Larry Silver, M.D., is clinical professor of psychiatry at Georgetown Medical Center in Washington, D.C. and director of training in child and adolescent psychiatry at Georgetown University School of Medicine. He is a former acting director and deputy director of the National Institute of Mental Health, as well as the author of Dr. Larry Silver's Advice to Parents on AD/HD and The Misunderstood Child: Understanding and Coping with Your Child's Learning Disabilities.
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