My son is also on a Straterra/Concerta combination. Concerta didn't work well enough by itself, and we added the Straterra because he couldn't tolerate higher doses of the Concerta. We're up to Concerta 27/Straterra 40. This combination seems to be working well for him, but he does get moody at times. It's not all the time, though. You might want to give it another week for him to get used to the combination dose. You also may be interested in this link about Straterra side effects http://www.strattera.ws/ I don't know what other factors there are in your son's diagnosis, so this combination may not be right for him. I took my son to a pediatric neurologist and she is the one who manages his meds -- that's the best thing I ever did. I have realized that there is no better Dr. than a neurologist to treat this kind of brain disorder, especially since brain chemistry is so individual. She is well informed about the latest and greatest research and treatments, and always knows exactly what to do and what to try next when meds don't seem to be working. Has your Dr. had your son's blood tested for liver ALT/AST levels? Straterra has also been known to increase this in some people, and I don't know if all doctors are aware of this.

I would call the Dr. that prescribed it right away and let him/her know what kind of mood swings your son is having. There may be something else they can prescribe or adjust the dose. Good luck!

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