A new study shows that mixing antidepressants with mood stabilizers has minimal effect in treating bipolar depression.
Adding antidepressants to mood-stabilizing drugs may not help — or hurt — the treatment of bipolar depression, the depressive phase of bipolar disorder.
Researchers report that news online in The New England Journal of Medicine. They included Gary Sachs, M.D., of Massachusetts General Hospital and Harvard Medical School.
The study's results "indicate that careful management of mood-stabilizer medications is a reasonable alternative to adding antidepressant medication for treating bipolar depression," Sachs says in a news release from the National Institute of Mental Health.